PRMT1 Contributes to HNF1A‐AS1‐mediated Regulation Network of CYP3A4 in Huh7 Cells
نویسندگان
چکیده
منابع مشابه
CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells.
Drug-induced hepatotoxicity is an important cause for disapproval, limitations of use, or withdrawal of drugs, and there is a high need for reproducible in vitro systems that can predict such toxicity. In this study, we show that confluent growth of the human hepatoma cell line Huh7 up to 5 weeks results in increased gene expression of several cytochromes P450 (P450s), UDP-glucuronosyltransfera...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2021
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2021.35.s1.03387